Selectively targeting the gut in inflammatory bowel disease: Targeting integrins
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چکیده
منابع مشابه
Colonic Drug Targeting Approaches for Treatment of Inflammatory Bowel Disease
Occurrence of inflammatory bowel diseases has increased at an alarming rate. The predominant inflammatory bowel diseases are Ulcerative colitis and Crohn’s disease. The treatment and extent of therapy is decided by the severity of the conditions. The most common drugs prescribed in the treatment include anti-inflammatory agents like 5 amino salicylates, corticosteroids and immunosuppressants. C...
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The gut mucosal barrier plays an important role in maintaining a delicate immune homeostasis. The pathogenesis of inflammatory bowel disease (IBD) is considered to involve a defective mucosal immunity along with a genetic predisposition. Recent views have suggested an excessive response to components of the gut microbiota in IBD. A condition of "dysbiosis", with alterations of the gut microbial...
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ژورنال
عنوان ژورنال: Journal of Gastroenterology and Hepatology
سال: 2018
ISSN: 0815-9319
DOI: 10.1111/jgh.14431